Anti-SHMT antibodies enable researchers to detect and measure the SHMT antigen in biological samples. This target is a reported synonym of the SHMT1 gene, which encodes serine hydroxymethyltransferase 1. This protein is known to function in metabolic processes, among other biological roles. The human version of SHMT has a canonical amino acid length of 483 residues and a protein mass of 53.1 kilodaltons, although 4 isoforms have been identified. It is reported to be localized in the cytoplasm of cells and widely expressed in many tissue types. SHMT is a member of the SHMT protein family.