Anti-MACH antibodies enable researchers to detect and measure the MACH antigen in biological samples. This target is a reported synonym of the CASP8 gene, which encodes caspase 8. This protein is known to function in the apoptotic pathway and angiogenesis, among other biological roles. The human version of MACH has a canonical amino acid length of 479 residues and a protein mass of 55.4 kilodaltons, although 9 isoforms have been identified. It is reported to be localized in the nucleus and cytoplasm of cells and widely expressed in many tissue types. Other names for this target antigen include ALPS2B, CAP4, and FLICE. A number of MACH antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.