Anti-KMT5C antibodies are used in the immunodetection of the protein lysine methyltransferase 5C. In humans, the canonical protein has a reported length of 462 amino acid residues and a mass of 52.1 kDa. Its subcellular localization is in the nucleus. Up to 2 different isoforms have been reported for this protein. A member of the Histone-lysine methyltransferase protein family, KMT5C is a known histone methyltransferase that specifically methylates monomethylated 'Lys-20' (H4K20me1) and dimethylated 'Lys-20' (H4K20me2) of histone H4 to produce respectively dimethylated 'Lys-20' (H4K20me2) and trimethylated 'Lys-20' (H4K20me3) and thus regulates transcription and maintenance of genome integrity. Synonyms for this target antigen include [histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B, [histone H4]-lysine20 N-methyltransferase KMT5B, histone-lysine N-methyltransferase SUV420H2, and histone-lysine N-methyltransferase KMT5C. KMT5C gene orthologs have been reported in the mouse, rat, bovine, frog and chimpanzee species. Western Blot is a widely used application for the KMT5C antibodies listed below. In addition, ELISA is also a common application.