Pmel17, or Premelanosome protein, is a human gene encoded by PMEL. It may also be known as: Melanocyte protein PMEL; ME20-M; ME20M; Melanocyte protein Pmel 17; Melanocytes lineage-specific antigen GP100; Melanoma-associated ME20 antigen; Silver locus protein homolog; D12S53E; ME20; PMEL17; SILV; gp100. The encoded protein has an amino acid length of 661 and a mass of 70.3 kDa. Other isoforms may exist. Pmel17 is a member of the PMEL/NMB family. Homologs of this gene exist in other organisms, including: Mouse, Frog.