Anti-SHC1 antibodies are used in the immunodetection of the protein SHC adaptor protein 1. In humans, the canonical protein has a reported length of 583 amino acid residues and a mass of 62.8 kDa. Its subcellular localization is in the mitochondria and cytoplasm. Up to 6 different isoforms have been reported for this protein. It is widely expressed across many tissue types. SHC1 is reported to be a signaling adapter that couples activated growth factor receptors to signaling pathways. Synonyms for this target antigen include SHCA, SHC-transforming protein 1, SH2 domain protein C1, SHC (Src homology 2 domain containing) transforming protein 1, SHC-transforming protein 3, and SHC. SHC1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 140 citations in the literature describe the use of SHC1 antibodies in research. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.