Anti-NUDT4 antibodies are used in the immunodetection of the protein nudix hydrolase 4. In humans, the canonical protein has a reported length of 180 amino acid residues and a mass of 20.3 kDa. Its subcellular localization is in the cytoplasm. Up to 3 different isoforms have been reported for this protein. It is reported to be expressed in the heart and, at lower level in skeletal muscle, pancreas and kidney. A member of the Nudix hydrolase protein family, NUDT4 is known to be involved with intracellular signal transduction.
The NUDT4 marker can be used to identify Lymphatic Vessel Endothelial Cells and Subcapsular Sinus Ceiling Lymphatic Endothelial Cells.* Synonyms for this target antigen include DIPP2, DIPP2alpha, DIPP2beta, HDCMB47P, NUDT4B, and DIPP-2B. NUDT4 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Western Blot is a widely used application for the NUDT4 antibodies listed below. In addition, ELISA is also a common application.
*HuBMAP Human Reference Atlas v1.4