Anti-MBIP antibodies are used in the immunodetection of the protein MAP3K12 binding inhibitory protein 1. In humans, the canonical protein has a reported length of 344 amino acid residues and a mass of 39.3 kDa. Its subcellular localization is in the nucleus and cytoplasm. Alternative splicing is reported to yield 4 different isoforms for this protein. It is ubiquitously expressed across many tissue types. MBIP is reported to inhibit the MAP3K12 activity to induce the activation of the JNK/SAPK pathway. Synonyms for this target antigen include MAPK upstream kinase-binding inhibitory protein and MUK-binding inhibitory protein.