Anti-HIG1 antibodies enable researchers to detect and measure the HIG1 antigen in biological samples. This target is a reported synonym of the HIGD1A gene, which encodes HIG1 hypoxia inducible domain family member 1A. This protein is known to function in the regulation of apoptosis, among other biological roles. The human version of HIG1 has a canonical amino acid length of 93 residues and a protein mass of 10.1 kilodaltons, although 2 isoforms have been identified. It is reported to be localized in the mitochondria of cells and notably expressed in many tissues, such as the appendix and parathyroid gland.