Anti-PSMA8 antibodies are used in the immunodetection of the protein proteasome 20S subunit alpha 8. In humans, the canonical protein has a reported length of 256 amino acid residues and a mass of 28.5 kDa. Its subcellular localization is in the nucleus. Up to 3 different isoforms have been reported for this protein. A member of the Peptidase T1A protein family, PSMA8 is a known component of the spermatoproteasome, a proteasome specifically found in testis that promotes acetylation-dependent degradation of histones, thereby participating actively to the exchange of histones during spermatogenesis. Synonyms for this target antigen include alpha4s, proteasome (prosome, macropain) subunit, alpha type, 8, proteasome alpha 4 subunit, proteasome subunit alpha 8, and proteasome subunit alpha-type 8. PSMA8 gene orthologs have been reported in the mouse, rat, bovine and chimpanzee species. Some PSMA8 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.