Anti-ACSM2A antibodies are used in the immunodetection of the protein acyl-CoA synthetase medium chain family member 2A. In humans, the canonical protein has a reported length of 577 amino acid residues and a mass of 64.2 kDa. Its subcellular localization is in the mitochondria. It is notably expressed in the kidney and liver. A member of the ATP-dependent AMP-binding enzyme protein family, ACSM2A is known to catalyze the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism (By similarity).
The ACSM2A marker can be used to identify Proximal Tubule Segment 2 Epithelial Cells.* Synonyms for this target antigen include acyl-CoA synthetase medium-chain family member 2, benzoate--CoA ligase, butyrate--CoA ligase 2A, butyryl-coenzyme A synthetase 2A, and acyl-coenzyme A synthetase ACSM2A, mitochondrial. ACSM2A gene orthologs have been reported in the mouse, rat and chimpanzee species. Some ACSM2A antibodies may have been used in research and have associated citations. These antibodies are most commonly used in Western Blot experiments, among other applications.
*HuBMAP Human Reference Atlas v1.4