Anti-Stanniocalcin 1 antibodies are used for the immunodetection of the protein encoded by the STC1 gene. In humans, the canonical protein has a reported length of 247 amino acid residues and a mass of 27.6 kDa. It is known to be a secreted protein. Alternative splicing is reported to yield 2 different isoforms for this protein. It is reported to be expressed in most tissues, with the highest levels in ovary, prostate, heart, kidney and thyroid. A member of the Stanniocalcin protein family, it is known to be involved with bone development and the cellular response to hypoxia. Post-translational modifications have been described, including glycosylation.
The stanniocalcin 1 marker can be used to characterize Ureter Myofibroblast Cells and Bladder Myofibroblast Cells.* Other names for this target antigen include STC. Gene orthologs have been identified in the mouse, rat, bovine, frog, chimpanzee and chicken species. A number of Stanniocalcin 1 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4