Anti-Merlin antibodies are used in antigen-specific immunodetection in biological samples. The target Merlin is a known alias name of the protein NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor, encoded by the NF2 gene in humans. This 595-amino acid residue protein is a suspected regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. It is localized to the nucleus and membrane of the cell and features ubiquitinated and phosphorylated post-translational modifications. In terms of tissue expression, it is widely expressed across many tissue types. Other synonyms for Merlin include ACN, BANF, and SCH. Over 100 citations in the literature describe the use of Merlin antibodies in research. Western Blot is a widely used application for these antibodies. ELISA, Immunocytochemistry, Immunofluorescence, and Immunohistochemistry are also common applications.