Anti-KIR2DL3 antibodies are used in the immunodetection of the protein killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3. In humans, the canonical protein has a reported length of 341 amino acid residues and a mass of 37.9 kDa. Its subcellular localization is in the cell membrane. Up to 2 different isoforms have been reported for this protein. A member of the Immunoglobulin protein superfamily, KIR2DL3 is a known receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Post-translational modifications have been described, including glycosylation. Synonyms for this target antigen include CD158b, GL183, KIR-023GB, KIR-K7b, KIR-K7c, KIR2DL, KIR2DS5, and CD158B2. Over 180 citations in the literature describe the use of KIR2DL3 antibodies in research. Flow Cytometry is a widely used application for these antibodies. ELISA and Western Blot are also common applications.