Anti-THEMIS2 antibodies are used in the immunodetection of the protein thymocyte selection associated family member 2. In humans, the canonical protein has a reported length of 643 amino acid residues and a mass of 72 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 6 different isoforms have been reported for this protein. It is reported to be expressed in different endometrial adenocarcinoma cell lines and various other cell lines apart from the prostate cell line LNCaP and the ovarian cancer cell line BG1. A member of the Themis protein family, Themis2 is believed to constitute a control point in macrophage inflammatory response, promoting LPS-induced TLR4-mediated TNF production. Synonyms for this target antigen include ICB-1, ICB1, protein THEMIS2, basement membrane-induced, induced by contact to basement membrane 1 protein, and C1orf38. Some Themis2 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.