Anti-PIGG antibodies are used in the immunodetection of the protein phosphatidylinositol glycan anchor biosynthesis class G. In humans, the canonical protein has a reported length of 983 amino acid residues and a mass of 108.2 kDa. Its subcellular localization is in the ER. Up to 6 different isoforms have been reported for this protein. It is a member of the PIGG/PIGN/PIGO protein family. Post-translational modifications have been described, including glycosylation. The PIGG gene has been associated with the disease, Neurodevelopmental disorder with or without hypotonia, seizures, and cerebellar atrophy. Synonyms for this target antigen include GPI7, LAS21, MRT53, NEDHSCA, PRO4405, RLGS1930, GPI ethanolamine phosphate transferase 2, and EMM. PIGG gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some PIGG antibodies may have been used in research and have associated citations. These antibodies are most commonly used in Immunohistochemistry experiments, among other applications.