Anti-EDEM3 antibodies are used in the immunodetection of the protein ER degradation enhancing alpha-mannosidase like protein 3. In humans, the canonical protein has a reported length of 932 amino acid residues and a mass of 104.7 kDa. Its subcellular localization is in the ER. Up to 2 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the Glycosyl hydrolase 47 protein family, EDEM3 is known to be involved in endoplasmic reticulum-associated degradation (ERAD). The EDEM3 gene has been associated with the disease, Congenital disorder of glycosylation. Synonyms for this target antigen include ER degradation-enhancing -mannosidase-like protein 3, ER degradation-enhancing alpha-mannosidase-like 3, alpha-1,2-mannosidase EDEM3, and ER degradation enhancer, mannosidase alpha-like 3. A number of EDEM3 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.