Anti-OGT antibodies are used in the immunodetection of the protein O-linked N-acetylglucosamine (GlcNAc) transferase. In humans, the canonical protein has a reported length of 1046 amino acid residues and a mass of 116.9 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 4 different isoforms have been reported for this protein. It is reported to be highly expressed in the pancreas and to a lesser extent in skeletal muscle, heart, brain and placenta. A member of the Glycosyltransferase 41 protein family, OGT is known to catalyze the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in cytoplasmic and nuclear proteins resulting in their modification with a beta-linked N-acetylglucosamine (O-GlcNAc). Synonyms for this target antigen include HRNT1, MRX106, O-GLCNAC, OGT1, XLID106, and HINCUT-1. OGT gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Over 220 citations in the literature describe the use of OGT antibodies in research. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.