Anti-PRR7 antibodies are used in the immunodetection of the protein proline rich 7, synaptic. In humans, the canonical protein has a reported length of 274 amino acid residues and a mass of 30.9 kDa. Its subcellular localization is in the cell membrane, nucleus, and cytoplasm. Up to 2 different isoforms have been reported for this protein. PRR7 is known to act as a synapse-to-nucleus messenger to promote NMDA receptor-mediated excitotoxicity in neurons in a JUN-dependent manner (By similarity). Post-translational modifications have been described, including palmitoylation and phosphorylation. Synonyms for this target antigen include proline-rich protein 7 and synaptic proline-rich membrane protein. PRR7 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some PRR7 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, Immunocytochemistry is also a common application.