Anti-PRPF8 antibodies are used in the immunodetection of the protein pre-mRNA processing factor 8. In humans, the canonical protein has a reported length of 2335 amino acid residues and a mass of 273.6 kDa. Its subcellular localization is in the nucleus. It is widely expressed across many tissue types. PRPF8 is known to play a role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes, both of the predominant U2-type spliceosome and the minor U12-type spliceosome. The PRPF8 gene has been associated with the disease, Retinitis pigmentosa. Synonyms for this target antigen include PRP8, PRPC8, RP13, SNRNP220, pre-mRNA-processing-splicing factor 8, and HPRP8. PRPF8 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of Prpf8 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.