Anti-PDE3A antibodies are used in the immunodetection of the protein phosphodiesterase 3A. In humans, the canonical protein has a reported length of 1141 amino acid residues and a mass of 125 kDa. Its subcellular localization is in the membrane and cytoplasm. It is notably expressed in many tissues, such as the bronchus, stomach, and appendix. A member of the Cyclic nucleotide phosphodiesterase protein family, PDE3A is known to be involved with the apoptotic pathway and GPCR signaling pathways.
The PDE3A marker can be used to identify Hypothalamus Splatter Neurons.* Synonyms for this target antigen include CGI-PDE A, CGI-PDE-A, HTNB, cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A, and CGI-PDE. PDE3A gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of PDE3A antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.
*HuBMAP Human Reference Atlas v1.4