Anti-GRM2 antibodies are used in the immunodetection of the protein glutamate metabotropic receptor 2. In humans, the canonical protein has a reported length of 872 amino acid residues and a mass of 95.6 kDa. Its subcellular localization is in the cell membrane. It is notably expressed in the brain cortex. A member of the G-protein coupled receptor 3 protein family, GRM2 is known to be involved with chemical synaptic transmission. Post-translational modifications have been described, including glycosylation. Synonyms for this target antigen include GPRC1B, MGLUR2, mGlu2, metabotropic glutamate receptor 2, glutamate receptor homolog, and GLUR2. GRM2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of GRM2 antibodies have been mentioned in research publications and have associated citations. Immunohistochemistry is a widely used application for these antibodies. In addition, Western Blot is also a common application.