Anti-TMEM8B antibodies are used in the immunodetection of the protein transmembrane protein 8B. In humans, the canonical protein has a reported length of 472 amino acid residues and a mass of 51.9 kDa. Its subcellular localization is in the cell membrane, nucleus, mitochondria, ER, and cytoplasm. Up to 3 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the TMEM8 protein family, TMEM8B is believed to function as a a regulator of the EGFR pathway. Post-translational modifications have been described, including N-glycosylation. Synonyms for this target antigen include FP588, LINC00950, NAG-5, NAG5, NGX6, NGX6a, nasopharyngeal carcinoma expressed 6, and C9orf127. TMEM8B gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Western Blot, Immunofluorescence, and Immunohistochemistry are common applications for TMEM8B antibodies.