Anti-EYS antibodies are used in the immunodetection of the protein eyes shut homolog. In humans, the canonical protein has a reported length of 3165 amino acid residues and a mass of 350.8 kDa. Up to 4 different isoforms have been reported for this protein. It is notably expressed in retina. A member of the EYS protein family, EYS is known to be required to maintain the integrity of photoreceptor cells. Post-translational modifications have been described, including glycosylation.
The EYS marker can be used to identify Brain CA4 Neurons.* Synonyms for this target antigen include EGF-like-domain, multiple 10, EGF-like-domain, multiple 11, epidermal growth factor-like protein 10, epidermal growth factor-like protein 11, protein spacemaker homolog, and protein eyes shut homolog. EYS gene orthologs have been reported in the zebrafish and chimpanzee species. A number of EYS antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.
*HuBMAP Human Reference Atlas v1.4