Anti-FLII antibodies are used in the immunodetection of the protein FLII actin remodeling protein. In humans, the canonical protein has a reported length of 1269 amino acid residues and a mass of 144.8 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 3 different isoforms have been reported for this protein. It is reported to be highly expressed in skeletal muscle with high expression also in the heart and lung. FLII is believed to play a role as coactivator in transcriptional activation by hormone-activated nuclear receptors (NR) and acts in cooperation with NCOA2 and CARM1. Synonyms for this target antigen include FLIL, Fli1, protein flightless-1 homolog, flightless I actin binding protein, flightless I homolog, and FLI. FLII gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish and chicken species. A number of FLII antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.