Anti-ORC5 antibodies are used in the immunodetection of the protein origin recognition complex subunit 5. In humans, the canonical protein has a reported length of 435 amino acid residues and a mass of 50.3 kDa. Its subcellular localization is in the nucleus and chromosomes. Up to 2 different isoforms have been reported for this protein. It is notably expressed in spleen, ovary, prostate, testis, and colon mucosa. A member of the ORC5 protein family, ORC5 is a known component of the origin recognition complex (ORC) that binds origins of replication. Post-translational modifications have been described, including ubiquitination. Synonyms for this target antigen include ORC5P, ORC5T, PPP1R117, protein phosphatase 1, regulatory subunit 117, and ORC5L. ORC5 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some ORC5 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.