SPB3, or Heat shock protein family B (small) member 3, is a human gene encoded by HSPB3. It may also be known as: Heat shock protein beta-3; HspB3; Heat shock 17 kDa protein; HSP 17; Protein 3; DHMN2C; HMN2C; HSPL27; heat shock 27kDa protein 3. The encoded protein has an amino acid length of 150 and a mass of 17.0 kDa. SPB3 is a member of the Small heat shock protein (HSP20) family. Homologs of this gene exist in other organisms, including: Mouse, Rat, Zebrafish, Frog, Chicken.