Anti-PPP3CA antibodies are used in the immunodetection of the protein protein phosphatase 3 catalytic subunit alpha. In humans, the canonical protein has a reported length of 521 amino acid residues and a mass of 58.7 kDa. Its subcellular localization is in the cell membrane and cytoplasm. Up to 5 different isoforms have been reported for this protein. It is reported to be expressed in keratinocytes. A member of the PPP phosphatase protein family, PPP3CA is known to be involved with pathways of aging and brain development. The PPP3CA gene has been associated with the disease, Epileptic encephalopathy. Synonyms for this target antigen include CALN, CALNA, CALNA1, CCN1, CNA1, DEE91, IECEE, and ACCIID. PPP3CA gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Over 110 citations in the literature describe the use of PPP3CA antibodies in research. Western Blot is a widely used application for these antibodies. Immunocytochemistry, Immunofluorescence, and Immunohistochemistry are also common applications.