Anti-arylformamidase antibodies are used in the immunodetection of the protein encoded by the AFMID gene. In humans, the canonical protein has a reported length of 303 amino acid residues and a mass of 34 kDa. Its subcellular localization is in the nucleus and cytoplasm. Alternative splicing is reported to yield 2 different isoforms for this protein. A member of the Kynurenine formamidase protein family, it is known to catalyze the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Other names for this target antigen include KFase, N-formylkynurenine formamidase, probable arylformamidase, and kynurenine formamidase.