Anti-EYA3 antibodies are used in the immunodetection of the protein EYA transcriptional coactivator and phosphatase 3. In humans, the canonical protein has a reported length of 573 amino acid residues and a mass of 62.7 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 5 different isoforms have been reported for this protein. A member of the EYA protein family, EYA3 is reported to be a tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). Post-translational modifications have been described, including phosphorylation. Synonyms for this target antigen include eyes absent homolog 3 and eyes absent 3. EYA3 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of EYA3 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.