Anti-LAPTM5 antibodies are used in the immunodetection of the protein lysosomal protein transmembrane 5. In humans, the canonical protein has a reported length of 262 amino acid residues and a mass of 29.9 kDa. Its subcellular localization is in the lysosomes. It is found to be highly expressed in adult hematopoietic tissues. A member of the LAPTM4/LAPTM5 transporter protein family, LAPTM5 is suspected to have a special functional role during embryogenesis and in adult hematopoietic cells.
The LAPTM5 marker can be used to identify Lymphatic Vessel Endothelial Cells.* Synonyms for this target antigen include lysosomal-associated transmembrane protein 5, CD40-ligand-activated specific transcripts, human retinoic acid-inducible E3 protein, and CLAST6. LAPTM5 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Some LAPTM5 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4