Anti-ISG20L2 antibodies are used in the immunodetection of the protein interferon stimulated exonuclease gene 20 like 2. In humans, the canonical protein has a reported length of 353 amino acid residues and a mass of 39.2 kDa. Its subcellular localization is in the nucleus. It is notably widely expressed in many tissue types. ISG20L2 is known to be a 3'-> 5'-exoribonuclease involved in ribosome biogenesis in the processing of the 12S pre-rRNA. Synonyms for this target antigen include interferon-stimulated 20 kDa exonuclease-like 2 and interferon stimulated exonuclease gene 20kDa like 2. ISG20L2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some ISG20L2 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.