Anti-TTYH3 antibodies are used in the immunodetection of the protein tweety family member 3. In humans, the canonical protein has a reported length of 523 amino acid residues and a mass of 57.5 kDa. Its subcellular localization is in the cell membrane. Up to 4 different isoforms have been reported for this protein. It is reported to be expressed in excitable tissues. A member of the Tweety protein family, TTYH3 is a suspected large-conductance Ca(2+)-activated chloride channel. Post-translational modifications have been described, including N-glycosylation. Synonyms for this target antigen include hTTY3, tweety homolog 3, and protein tweety homolog 3. TTYH3 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some TTYH3 antibodies may have been used in research and have associated citations. These antibodies are most commonly used in Western Blot experiments, among other applications.