Nucleostemin, or Guanine nucleotide binding protein-like 3 (nucleolar), is a human gene encoded by GNL3. It may also be known as: Guanine nucleotide-binding protein-like 3; E2-induced gene 3 protein; Novel nucleolar protein 47; NNP47; Nucleolar GTP-binding protein 3; C77032; E2IG3. The encoded protein has an amino acid length of 549 and a mass of 62.0 kDa. Nucleostemin is a member of the TRAFAC class YlqF/YawG GTPase family. Homologs of this gene exist in other organisms, including: Frog.