Anti-PIGU antibodies are used in the immunodetection of the protein phosphatidylinositol glycan anchor biosynthesis class U. In humans, the canonical protein has a reported length of 435 amino acid residues and a mass of 50.1 kDa. Its subcellular localization is in the ER. Up to 2 different isoforms have been reported for this protein. A member of the PIGU protein family, PIGU is a known component of the GPI transamidase complex. The PIGU gene has been associated with the disease, Neurodevelopmental disorder with brain anomalies, seizures, and scoliosis. Synonyms for this target antigen include CDC91 (cell division cycle 91, S. cerevisiae, homolog)-like 1, GPI and Actin Bar homolog, GPI transamidase component PIG-U, and phosphatidylinositol glycan anchor biosynthesis class U protein. PIGU gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some PIGU antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.