Anti-F2RL2 antibodies are used in the immunodetection of the protein coagulation factor II thrombin receptor like 2. In humans, the canonical protein has a reported length of 374 amino acid residues and a mass of 42.5 kDa. Its subcellular localization is in the cell membrane. Up to 2 different isoforms have been reported for this protein. It is reported to be highly expressed in the megakaryocytes of the bone marrow, lower in mature megakaryocytes, in platelets and in a variety of other tissues such as heart and gut. A member of the G-protein coupled receptor 1 protein family, F2RL2 is a known receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. Synonyms for this target antigen include PAR3, proteinase-activated receptor 3, Coagulation factor II receptor-like 2 (protease-actovated receptor 3), protease-activated receptor 3, thrombin receptor-like 2, and PAR-3. A number of F2RL2 antibodies have been mentioned in research publications and have associated citations. Immunohistochemistry is a widely used application for these antibodies. ELISA, Western Blot, and Immunofluorescence are also common applications.