Anti-HHF3 antibodies enable researchers to detect and measure the HHF3 antigen in biological samples. This target is a reported synonym of the GCK gene, which encodes glucokinase. This protein is known to function in insulin signaling pathways and carbohydrate metabolism and homeostasis, among other biological roles. The human version of HHF3 has a canonical amino acid length of 465 residues and a protein mass of 52.2 kilodaltons, although 3 isoforms have been identified. It is reported to be localized in the nucleus, mitochondria, and cytoplasm of cells and widely expressed in many tissue types. Other names for this target antigen include FGQTL3, GK, and GLK. Some HHF3 antibodies may have been used in research and have associated citations. Immunocytochemistry is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.