Anti-CHMP2B antibodies are used in the immunodetection of the protein charged multivesicular body protein 2B. In humans, the canonical protein has a reported length of 213 amino acid residues and a mass of 23.9 kDa. Its subcellular localization is in the membrane and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is widely expressed across many tissue types. A member of the SNF7 protein family, Chmp2b is a suspected core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. Synonyms for this target antigen include CHMP2.5, DMT1, FTDALS7, VPS2-2, VPS2B, VPS2 homolog B, chromatin modifying protein 2B, and ALS17. CHMP2B gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of Chmp2b antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.