Anti-AMY2A antibodies are used in the immunodetection of the protein amylase alpha 2A. In humans, the canonical protein has a reported length of 511 amino acid residues and a mass of 57.7 kDa. It has been described to be a secreted protein. Up to 2 different isoforms have been reported for this protein. It is notably expressed in the pancreas. A member of the Glycosyl hydrolase 13 protein family, AMY2A is known to be involved with carbohydrate metabolism and homeostasis. Post-translational modifications have been described, including glycosylation.
The AMY2A marker can be used to identify Pancreas Exocrine Glandular Cells.* Synonyms for this target antigen include PA, 1,4-alpha-D-glucan glucanohydrolase, amylase alpha 2A (pancreatic), glycogenase, and AMY2. A number of amy2a antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.
*HuBMAP Human Reference Atlas v1.4