Anti-TM2D1 antibodies are used in the immunodetection of the protein TM2 domain containing 1. In humans, the canonical protein has a reported length of 207 amino acid residues and a mass of 22.3 kDa. Its subcellular localization is in the membrane. It is widely expressed across many tissue types. A member of the TM2 protein family, Tm2d1 is believed to participate in amyloid-beta-induced apoptosis via its interaction with beta-APP42. Post-translational modifications have been described, including N-glycosylation. Synonyms for this target antigen include Beta-amyloid peptide binding protein, amyloid-beta-binding protein, beta-amyloid-binding protein, hBBP, and TM2 domain-containing protein 1. TM2D1 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. These Tm2d1 antibodies are widely used in Western Blot experiments, among other applications.