Anti-TMX3 antibodies are used in the immunodetection of the protein thioredoxin related transmembrane protein 3. In humans, the canonical protein has a reported length of 454 amino acid residues and a mass of 51.9 kDa. Its subcellular localization is in the ER. Up to 2 different isoforms have been reported for this protein. It is widely expressed across many tissue types. A member of the Protein disulfide isomerase protein family, TMX3 is a suspected disulfide isomerase, which participates in the folding of proteins containing disulfide bonds. Post-translational modifications have been described, including N-glycosylation. Synonyms for this target antigen include TXNDC10, protein disulfide-isomerase TMX3, protein disulfide isomerase family A, member 13, thioredoxin domain containing 10, thioredoxin domain-containing protein 10, and PDIA13. TMX3 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. ELISA, Western Blot, and Immunohistochemistry are common applications for TMX3 antibodies.