Anti-IL36G antibodies are used in the immunodetection of the protein interleukin 36 gamma. In humans, the canonical protein has a reported length of 169 amino acid residues and a mass of 18.7 kDa. Its subcellular localization is in the cytoplasm and is secreted. Up to 2 different isoforms have been reported for this protein. It is reported to be highly expressed in tissues containing epithelial cells: skin, lung, stomach and esophagus. A member of the IL-1 protein family, IL36G is a reported to be a cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Synonyms for this target antigen include IL-1-epsilon, interleukin 1-related protein 2, interleukin-1 epsilon, interleukin-1 family member 9, interleukin-1 homolog 1, and IL-1 related protein 2. IL36G gene orthologs have been reported in the mouse, bovine and chimpanzee species. A number of IL36G antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.