Anti-Granzyme K antibodies are used in the immunodetection of the protein encoded by the GZMK gene. In humans, the canonical protein has a reported length of 264 amino acid residues and a mass of 28.9 kDa. Its subcellular localization is in the cytoplasm and is also secreted. It is reported to be expressed in the lung, spleen, thymus and peripheral blood leukocytes. A member of the Peptidase S1 protein family, it is known to be involved with proteolysis. Other names for this target antigen include NK-Tryp-2, NK-tryptase-2, fragmentin-3, granzyme 3, granzyme K (granzyme 3; tryptase II), and TRYP2.