Anti-CMTM8 antibodies are used in the immunodetection of the protein CKLF like MARVEL transmembrane domain containing 8. In humans, the canonical protein has a reported length of 173 amino acid residues and a mass of 19.6 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is reported to be highly expressed in the liver and pancreas. A member of the Chemokine-like factor protein family, CMTM8 is known to be involved with chemotaxis.
The CMTM8 marker can be used to identify Deep-Layer Intratelencephalic Neurons, Brain Splatter Neurons, Hippocampal Gyrus Chandelier Neurons, and Gray Matter CGE Interneurons.* Synonyms for this target antigen include chemokine-like factor superfamily member 8, and CKLF-like MARVEL transmembrane domain-containing protein 8. CMTM8 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some CMTM8 antibodies may have been used in research and have associated citations. Immunohistochemistry is a widely used application for these antibodies. ELISA, Western Blot, and Immunofluorescence are also common applications.
*HuBMAP Human Reference Atlas v1.4