Anti-MCC antibodies are used in the immunodetection of the protein MCC regulator of WNT signaling pathway. In humans, the canonical protein has a reported length of 829 amino acid residues and a mass of 93 kDa. Its subcellular localization is in the cell membrane, nucleus, and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is reported to be expressed in a variety of tissues. A member of the MCC protein family, MCC is known to be the candidate for the putative colorectal tumor suppressor gene located at 5q21. Synonyms for this target antigen include colorectal mutant cancer protein, MCC, WNT signaling pathway regulator, mutated in colorectal cancers, and MCC1. MCC gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some MCC antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.