Anti-BIN2 antibodies are used in the immunodetection of the protein bridging integrator 2. In humans, the canonical protein has a reported length of 565 amino acid residues and a mass of 61.9 kDa. Its subcellular localization is in the membrane and cytoplasm. Up to 3 different isoforms have been reported for this protein. It is notably expressed in natural killer cells. BIN2 is reported to promote cell motility and migration, probably via its interaction with the cell membrane and with podosome proteins that mediate interaction with the cytoskeleton. Synonyms for this target antigen include breast cancer associated protein BRAP1, breast cancer-associated protein 1, and BRAP-1. BIN2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some BIN2 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.