Anti-LOX5 antibodies are protein reagents that detect specific antigens. The LOX5 antigen is another term for the human protein arachidonate 5-lipoxygenase, encoded by the ALOX5 gene. The protein is known to catalyze the oxygenation of arachidonate ((5Z,8Z,11Z,14Z)-eicosatetraenoate) to 5-hydroperoxyeicosatetraenoate (5-HPETE) followed by the dehydration to 5,6- epoxyeicosatetraenoate (Leukotriene A4/LTA4), the first two steps in the biosynthesis of leukotrienes, which are potent mediators of inflammation. Canonically, it has an amino acid length of 674 residues and a mass of 78 kilodaltons. Its subcellular localization is in the membrane, nucleus, and cytoplasm and it is expressed in many tissues, such as the caudate and cerebellum. The LOX5 protein is a member of the Lipoxygenase protein family.