Anti-fas ligand antibodies are used for the immunodetection of the protein encoded by the FASLG gene. In humans, the canonical protein has a reported length of 281 amino acid residues and a mass of 31.5 kDa. Its subcellular localization is in the cytoplasmic vesicles, lysosomes, and cell membrane. Alternative splicing is reported to yield 2 different isoforms for this protein. A member of the Tumor necrosis factor protein family, it is a reported to be a cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. Other names for this target antigen include APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6, and ALPS1B. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 330 citations in the literature describe the use of fas ligand antibodies in research. Flow Cytometry is a widely used application for these antibodies. ELISA and Western Blot are also common applications.