Fig 1: Silent information regulator 1 (SIRT1) regulates Fas ligand (FasL), caspase-3 and p53 expression in CD4+ T cells. (A) The gated dot plots indicate the frequency of FasL-expressing CD4+ T cells. (B) The gated dot plots indicate the frequency of caspase-3-expressing CD4+ T cells. (a1 and b1) Cells from the control group; (a2 and b2) cells from the allergic rhinitis (AR) group; (a3 and b3) cells from the AR group and CD4+ T cells were cultured with sirtinol (SIRT1 antagonist); (a4 and b4) cells from the AR group and CD4+ T cells were stimulated with resveratrol (SIRT1 agonist). (C) The bars indicate the summarized frequencies of (A). (D) The bars indicate the summarized frequencies of (B). (E) The immune blots indicate the p53 protein levels in CD4+ T cells. The bars below the blots indicate the integrated density of the immune blots. The data are presented as mean ± standard deviation. *P<0.05 compared with control; #P<0.05 compared with AR.