Anti-SLC17A1 antibodies are used in the immunodetection of the protein solute carrier family 17 member 1. In humans, the canonical protein has a reported length of 467 amino acid residues and a mass of 51.1 kDa. Its subcellular localization is in the cell membrane. Up to 2 different isoforms have been reported for this protein. It is reported to be expressed in the kidney cortex, liver and brain but not in other tissues. A member of the Sodium/anion cotransporter protein family, SLC17A1 is known to be important for the resorption of phosphate by the kidney. Post-translational modifications have been described, including glycosylation. The SLC17A1 marker can be used to identify Proximal Tubule Segment 3 Epithelial Cells.* Synonyms for this target antigen include NPT-1, NPT1, sodium-dependent phosphate transport protein 1, Na(+)/PI cotransporter 1, na/Pi-4, and NAPI-1. SLC17A1 gene orthologs have been reported in the mouse, rat, bovine and chimpanzee species.
*HuBMAP Human Reference Atlas v1.4