Anti-P2RX6 antibodies are used in the immunodetection of the protein purinergic receptor P2X 6. In humans, the canonical protein has a reported length of 441 amino acid residues and a mass of 48.8 kDa. Its subcellular localization is in the membrane. Up to 2 different isoforms have been reported for this protein. It is reported to be highly expressed in skeletal muscle. A member of the P2X receptor protein family, P2RX6 is a known receptor for ATP that acts as a ligand-gated ion channel. Post-translational modifications have been described, including N-glycosylation. Synonyms for this target antigen include P2X6, P2XM, P2X purinoceptor 6, ATP receptor, purinergic receptor P2X, ligand gated ion channel, 6, and P2RXL1. P2RX6 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. A number of P2RX6 antibodies have been mentioned in research publications and have associated citations. These antibodies are most commonly used in Western Blot experiments, among other applications.